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Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures

Polycystin-2 (PC2), encoded by PKD2, which is one of the genes whose mutations cause polycystic kidney disease, is abundantly produced in the apical domain of the syncytiotrophoblast (hST) of term human placenta. PC2, a TRP-type (TRPP2) non-selective cation channel, is present in primary cilia of re...

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Autores principales: Montalbetti, Nicolás, Li, Qiang, Wu, Yuliang, Chen, Xing-Zhen, Cantiello, Horacio F
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151358/
https://ncbi.nlm.nih.gov/pubmed/17204494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.125583
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