Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures

Polycystin-2 (PC2), encoded by PKD2, which is one of the genes whose mutations cause polycystic kidney disease, is abundantly produced in the apical domain of the syncytiotrophoblast (hST) of term human placenta. PC2, a TRP-type (TRPP2) non-selective cation channel, is present in primary cilia of re...

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Bibliografiske detaljer
Main Authors: Montalbetti, Nicolás, Li, Qiang, Wu, Yuliang, Chen, Xing-Zhen, Cantiello, Horacio F
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2007
Fag:
Cellular
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151358/
https://ncbi.nlm.nih.gov/pubmed/17204494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.125583
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