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Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures

Polycystin-2 (PC2), encoded by PKD2, which is one of the genes whose mutations cause polycystic kidney disease, is abundantly produced in the apical domain of the syncytiotrophoblast (hST) of term human placenta. PC2, a TRP-type (TRPP2) non-selective cation channel, is present in primary cilia of re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Montalbetti, Nicolás, Li, Qiang, Wu, Yuliang, Chen, Xing-Zhen, Cantiello, Horacio F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151358/
https://ncbi.nlm.nih.gov/pubmed/17204494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.125583
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