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Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures

Polycystin-2 (PC2), encoded by PKD2, which is one of the genes whose mutations cause polycystic kidney disease, is abundantly produced in the apical domain of the syncytiotrophoblast (hST) of term human placenta. PC2, a TRP-type (TRPP2) non-selective cation channel, is present in primary cilia of re...

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Detalhes bibliográficos
Main Authors: Montalbetti, Nicolás, Li, Qiang, Wu, Yuliang, Chen, Xing-Zhen, Cantiello, Horacio F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151358/
https://ncbi.nlm.nih.gov/pubmed/17204494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.125583
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