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Identification of yeast tRNA Um(44) 2′-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species

A characteristic feature of tRNAs is the numerous modifications found throughout their sequences, which are highly conserved and often have important roles. Um(44) is highly conserved among eukaryotic cytoplasmic tRNAs with a long variable loop and unique to tRNA(Ser) in yeast. We show here that the...

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Detalles Bibliográficos
Main Authors: Kotelawala, Lakmal, Grayhack, Elizabeth J., Phizicky, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151035/
https://ncbi.nlm.nih.gov/pubmed/18025252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.811008
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