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tRNA m(7)G methyltransferase Trm8p/Trm82p: Evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p

We show that Saccharomyces cerevisiae strains lacking Trm8p/Trm82p tRNA m(7)G methyltransferase are temperature-sensitive in synthetic media containing glycerol. Bacterial TRM8 orthologs complement the growth defect of trm8-Δ, trm82-Δ, and trm8-Δ trm82-Δ double mutants, suggesting that bacteria empl...

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Bibliografski detalji
Glavni autori: ALEXANDROV, ANDREI, GRAYHACK, ELIZABETH J., PHIZICKY, ERIC M.
Format: Artigo
Jezik:Inglês
Izdano: Copyright 2005 by RNA Society 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370766/
https://ncbi.nlm.nih.gov/pubmed/15811913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2030705
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