The N domain of Smad7 is essential for specific inhibition of transforming growth factor-β signaling

Inhibitory Smads (I-Smads) repress signaling by cytokines of the transforming growth factor-β (TGF-β) superfamily. I-Smads have conserved carboxy-terminal Mad homology 2 (MH2) domains, whereas the amino acid sequences of their amino-terminal regions (N domains) are highly divergent from those of oth...

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Detalhes bibliográficos
Main Authors: Hanyu, Aki, Ishidou, Yasuhiro, Ebisawa, Takanori, Shimanuki, Tomomasa, Imamura, Takeshi, Miyazono, Kohei
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150897/
https://ncbi.nlm.nih.gov/pubmed/11739411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200106023
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