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Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix

We used fluorescent speckle microscopy to probe the dynamics of the mitotic kinesin Eg5 in Xenopus extract spindles, and compared them to microtubule dynamics. We found significant populations of Eg5 that were static over several seconds while microtubules flux towards spindle poles. Eg5 dynamics ar...

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Autori principali: Kapoor, Tarun M., Mitchison, Timothy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150813/
https://ncbi.nlm.nih.gov/pubmed/11564753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200106011
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