Regulation of limb patterning by extracellular microfibrils

To elucidate the contribution of the extracellular microfibril–elastic fiber network to vertebrate organogenesis, we generated fibrillin 2 (Fbn2)–null mice by gene targeting and identified a limb-patterning defect in the form of bilateral syndactyly. Digit fusion involves both soft and hard tissues,...

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Bibliographic Details
Main Authors: Arteaga-Solis, Emilio, Gayraud, Barbara, Lee, Sui Y., Shum, Lillian, Sakai, Lynn, Ramirez, Francesco
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150751/
https://ncbi.nlm.nih.gov/pubmed/11470817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200105046
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