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Raltitrexed (Tomudex): an alternative drug for patients with colorectal cancer and 5-fluorouracil associated cardiotoxicity.

Two patients with proven 5-fluorouracil (5-FU)-associated cardiotoxicity were treated with the specific thymidylate synthase inhibitor raltitrexed safely, without evidence of cardiotoxicity. Raltitrexed might be an alternative for patients with advanced colorectal cancer and 5-FU-associated cardioto...

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Autores principales: Köhne, C. H., Thuss-Patience, P., Friedrich, M., Daniel, P. T., Kretzschmar, A., Benter, T., Bauer, B., Dietz, R., Dörken, B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150099/
https://ncbi.nlm.nih.gov/pubmed/9528843
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