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Phase II trial of raltitrexed ('Tomudex') in advanced small-cell lung cancer.

Raltitrexed, a thymidylate synthase inhibitor, was given to 21 patients with advanced small-cell lung cancer, at a dose of 3 mg m(-2) as a 15-min intravenous infusion at 21-day intervals. All of the patients had extensive disease and 17 had received prior therapy. Patients with disease refractory to...

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Hlavní autoři: Woll, P. J., Basser, R., Le Chevalier, T., Drings, P., Perez Manga, G., Adenis, A., Seymour, L., Smith, F., Thatcher, N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223947/
https://ncbi.nlm.nih.gov/pubmed/9231930
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