Effects of impaired renal function on the pharmacokinetics of raltitrexed (Tomudex ZD1694).

This open-label, non-randomized, parallel-group trial investigated the pharmacokinetics of raltitrexed (Tomudex, formerly ZD1694) after a single intravenous dose of 3.0 mg m(-2), comparing eight cancer patients with mild to moderate renal impairment (creatinine clearance 25-65 ml min(-1)) with eight...

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Detalhes bibliográficos
Main Authors: Judson, I., Maughan, T., Beale, P., Primrose, J., Hoskin, P., Hanwell, J., Berry, C., Walker, M., Sutcliffe, F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group|1 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062997/
https://ncbi.nlm.nih.gov/pubmed/9820178
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