A phase II study in advanced breast cancer: ZD1694 ('Tomudex') a novel direct and specific thymidylate synthase inhibitor.

ZD1694 ('Tomudex'), a novel, direct and specific thymidylate synthase (TS) inhibitor, was developed in a collaborative research programme between Zeneca Pharmaceuticals and the Institute of Cancer Research (UK) and entered clinical trials in 1991; phase II studies began in 1992, using 3.0...

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Main Authors: Smith, I., Jones, A., Spielmann, M., Namer, M., Green, M. D., Bonneterre, J., Wander, H. E., Hatschek, T., Wilking, N., Zalcberg, J., Spiers, J., Seymour, L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074654/
https://ncbi.nlm.nih.gov/pubmed/8695369
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