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Nitric oxide involvement in the toxicity of hydroxyguanidine in leukaemia HL60 cells.

The free-radical intermediates and the stable products formed on one-electron oxidation of hydroxyguanidine (HOG) were investigated in order to suggest a mechanistic basis for HOG-induced cytotoxicity and cytostasis in leukaemia HL60 cells. The azide radical (generated radiolytically) reacted with H...

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Detalhes bibliográficos
Main Authors: Everett, S. A., Smith, K. A., Patel, K. B., Dennis, M. F., Stratford, M. R., Wardman, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150015/
https://ncbi.nlm.nih.gov/pubmed/8763874
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