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IL-22 but not IL-17 provides protection to hepatocytes during acute liver inflammation

The cytokine IL-22 is primarily expressed by Th17 CD4 T cells and is highly upregulated during chronic inflammatory diseases. IL-22 receptor expression is absent on immune cells, but is instead restricted to the tissues, providing signaling directionality from the immune system to the tissues. Howev...

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Sonraí Bibleagrafaíochta
Main Authors: Zenewicz, Lauren A., Yancopoulos, George D., Valenzuela, David M., Murphy, Andrew J., Karow, Margaret, Flavell, Richard A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149911/
https://ncbi.nlm.nih.gov/pubmed/17919941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.07.023
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