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Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A

IL-22 has both proinflammatory and tissue-protective properties depending on the context in which it is expressed. However, the factors that influence the functional outcomes of IL-22 expression remain poorly defined. We demonstrate that after administration of a high dose of bleomycin that induces...

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Bibliographic Details
Main Authors: Sonnenberg, Gregory F., Nair, Meera G., Kirn, Thomas J., Zaph, Colby, Fouser, Lynette A., Artis, David
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882840/
https://ncbi.nlm.nih.gov/pubmed/20498020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092054
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