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IL-22 is required for Th17 cell–mediated pathology in a mouse model of psoriasis-like skin inflammation

Psoriasis is a chronic skin disease resulting from the dysregulated interplay between keratinocytes and infiltrating immune cells. We report on a psoriasis-like disease model, which is induced by the transfer of CD4(+)CD45RB(hi)CD25(–) cells to pathogen-free scid/scid mice. Psoriasis-like lesions ha...

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Detalhes bibliográficos
Main Authors: Ma, Hak-Ling, Liang, Spencer, Li, Jing, Napierata, Lee, Brown, Tom, Benoit, Stephen, Senices, Mayra, Gill, Davinder, Dunussi-Joannopoulos, Kyriaki, Collins, Mary, Nickerson-Nutter, Cheryl, Fouser, Lynette A., Young, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200300/
https://ncbi.nlm.nih.gov/pubmed/18202747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33263
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