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IL-22 but not IL-17 provides protection to hepatocytes during acute liver inflammation
The cytokine IL-22 is primarily expressed by Th17 CD4 T cells and is highly upregulated during chronic inflammatory diseases. IL-22 receptor expression is absent on immune cells, but is instead restricted to the tissues, providing signaling directionality from the immune system to the tissues. Howev...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2149911/ https://ncbi.nlm.nih.gov/pubmed/17919941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.07.023 |
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