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Exploiting tumour hypoxia and overcoming mutant p53 with tirapazamine.

Human solid tumours are composed of a significant proportion of hypoxic cells, i.e. cells with oxygen levels lower than those of normal tissues. Tumour hypoxic cells have been shown to have a negative impact on the response of solid tumours to radiation therapy and chemotherapy. However, these low c...

詳細記述

保存先:
書誌詳細
第一著者: Brown, J. M.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149884/
https://ncbi.nlm.nih.gov/pubmed/9647614
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