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Metronidazole (Flagyl), misonidazole (Ro 07-0582), iron, zinc and sulphur compounds in cancer therapy.

The nitro radiosensitizers, metronidazole and misonidazole, have been shown to react rapidly with the sulphydryl compounds cysteine and cysteamine in the presence of ferrous ions. Similar reactions occur in the presence of copper ions but these are much slower. The initial interactions of the drugs...

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Détails bibliographiques
Auteurs principaux: Bahnemann, D., Basaga, H., Dunlop, J. R., Searle, A. J., Willson, R. L.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1978
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149407/
https://ncbi.nlm.nih.gov/pubmed/277218
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