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The rationale for the development of improved hypoxic cell radiosensitizers.

This paper outlines the chemical background to the selection of compounds likely to be clinically superior to the nitroimidazoles currently being evaluated in cancer therapy. The most important chemical properties to consider are electron affinity and lipophilicity, and the quantification and predic...

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書誌詳細
主要な著者: Wardman, P., Clarke, E. D., Flockhart, I. R., Wallace, R. G.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149377/
https://ncbi.nlm.nih.gov/pubmed/277207
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