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Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific Oligosaccharide Structure

In Saccharomyces cerevisiae, transfer of N-linked oligosaccharides is immediately followed by trimming of ER-localized glycosidases. We analyzed the influence of specific oligosaccharide structures for degradation of misfolded carboxypeptidase Y (CPY). By studying the trimming reactions in vivo, we...

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Main Authors: Jakob, Claude A., Burda, Patricie, Roth, Jürgen, Aebi, Markus
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149342/
https://ncbi.nlm.nih.gov/pubmed/9732283
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