Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair

Monoubiquitination of FANCD2 and PCNA promotes DNA repair. It causes chromatin accumulation of FANCD2 and facilitates PCNA's recruitment of translesion polymerases to stalled replication. USP1, a protease that removes monoubiquitin from FANCD2 and PCNA, was thought to reverse the DNA damage res...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Oestergaard, Vibe H., Langevin, Frederic, Kuiken, Hendrik J., Pace, Paul, Niedzwiedz, Wojciech, Simpson, Laura J., Ohzeki, Mioko, Takata, Minoru, Sale, Julian E., Patel, Ketan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148256/
https://ncbi.nlm.nih.gov/pubmed/18082605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.09.020
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados