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Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair
Monoubiquitination of FANCD2 and PCNA promotes DNA repair. It causes chromatin accumulation of FANCD2 and facilitates PCNA's recruitment of translesion polymerases to stalled replication. USP1, a protease that removes monoubiquitin from FANCD2 and PCNA, was thought to reverse the DNA damage res...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cell Press
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2148256/ https://ncbi.nlm.nih.gov/pubmed/18082605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.09.020 |
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