Growth Factor–induced p42/p44 MAPK Nuclear Translocation and Retention Requires Both MAPK Activation and Neosynthesis of Nuclear Anchoring Proteins

Mitogen-activated protein kinases (p42/p44 MAPK, also called Erk2 and Erk1) are key mediators of signal transduction from the cell surface to the nucleus. We have previously shown that the activation of p42/p44 MAPK required for transduction of mitogenic signaling is associated with a rapid nuclear...

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Autores principales: Lenormand, Philippe, Brondello, Jean-Marc, Brunet, Anne, Pouysségur, Jacques
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148158/
https://ncbi.nlm.nih.gov/pubmed/9700154
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