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Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry.

Mitogen-activated protein kinase (MAPK) modules, composed of three protein kinases activated by successive phosphorylation, are involved in the signal transduction of a wide range of extracellular agents. In mammalian cells, mitogenic stimulation triggers the translocation of p42/p44MAPK from the cy...

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Detalhes bibliográficos
Main Authors: Brunet, A, Roux, D, Lenormand, P, Dowd, S, Keyse, S, Pouysségur, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171159/
https://ncbi.nlm.nih.gov/pubmed/9927426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.3.664
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