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MECHANISMS OF ACQUIRED RESISTANCE TO ENDOCRINE THERAPY IN HORMONE-DEPENDENT BREAST CANCER CELLS

Acquired resistance is a major problem limiting the clinical benefit of endocrine therapy. To investigate the mechanisms involved, two in vitro models were developed from MCF-7 cells. Long-term culture of MCF-7 cells in estrogen deprived medium (LTED) mimics aromatase inhibition in patients. Continu...

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Hlavní autoři: Yue, Wei, Fan, Ping, Wang, Jiping, Li, Yuebai, Santen, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2147683/
https://ncbi.nlm.nih.gov/pubmed/17616457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.05.008
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