ATM binds to β-adaptin in cytoplasmic vesicles

Inherited mutations in the ATM gene lead to a complex clinical phenotype characterized by neuronal degeneration, oculocutaneous telangiectasias, immune dysfunction, and cancer predisposition. Using the yeast two-hybrid system, we demonstrate that ataxia telangiectasia mutated (ATM) binds to β-adapti...

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Autors principals: Lim, Dae-Sik, Kirsch, David G., Canman, Christine E., Ahn, Jin-Hyun, Ziv, Yael, Newman, Lori S., Darnell, Robert B., Shiloh, Yosef, Kastan, Michael B.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21476/
https://ncbi.nlm.nih.gov/pubmed/9707615
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