Fragments of ATM which have dominant-negative or complementing activity.

The ATM protein has been implicated in pathways controlling cell cycle checkpoints, radiosensitivity, genetic instability, and aging. Expression of ATM fragments containing a leucine zipper motif in a human tumor cell line abrogated the S-phase checkpoint after ionizing irradiation and enhanced radi...

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Detalles Bibliográficos
Main Authors: Morgan, S E, Lovly, C, Pandita, T K, Shiloh, Y, Kastan, M B
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC232049/
https://ncbi.nlm.nih.gov/pubmed/9121450
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