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Neuregulin-1 Regulates Cell Adhesion via an ErbB2/Phosphoinositide-3 Kinase/Akt-Dependent Pathway: Potential Implications for Schizophrenia and Cancer

BACKGROUND: Neuregulin-1 (NRG1) is a putative schizophrenia susceptibility gene involved extensively in central nervous system development as well as cancer invasion and metastasis. Using a B lymphoblast cell model, we previously demonstrated impairment in NRG1α-mediated migration in cells derived f...

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Detalhes bibliográficos
Main Authors: Kanakry, Christopher G., Li, Zhen, Nakai, Yoko, Sei, Yoshitatsu, Weinberger, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2147048/
https://ncbi.nlm.nih.gov/pubmed/18159252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001369
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