Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides

Intracellular trafficking of major histocompatibility complex (MHC) class II molecules is characterized by passage through specialized endocytic compartment(s) where antigenic peptides replace invariant chain fragments in the presence of the DM protein. These changes are accompanied by structural tr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chervonsky, Alexander V., Medzhitov, Ruslan M., Denzin, Lisa K., Barlow, Avlin K., Rudensky, Alexander Yu., Janeway, Charles A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707606/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.10094
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