Minimum structural requirements for peptide presentation by major histocompatibility complex class II molecules: implications in induction of autoimmunity.

The precise mechanisms of failure of immunological tolerance to self proteins are not known. Major histocompatibility complex (MHC) susceptibility alleles, the target peptides, and T cells with anti-self reactivity must be present to cause autoimmune diseases. Experimental autoimmune encephalomyelit...

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Detalhes bibliográficos
Main Authors: Gautam, A M, Lock, C B, Smilek, D E, Pearson, C I, Steinman, L, McDevitt, H O
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43030/
https://ncbi.nlm.nih.gov/pubmed/7507253
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