Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins

Based on the promising opioid pharmacological profile of the peptide, Tyr-Pro-Trp-Gly-NH(2) (Tyr-W-MIF), Zadina et al. (1997) synthesized and screened other Gly(4)-substituted peptides, culminating in the synthesis of Tyr-Pro-Trp-Phe-NH(2) (endomorphin-1), which displayed high affinity and selectivi...

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Bibliografski detalji
Glavni autori: Terskiy, Alexandra, Wannemacher, Kenneth M., Yadav, Prem N., Tsai, Michael, Tian, Bin, Howells, Richard D.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144908/
https://ncbi.nlm.nih.gov/pubmed/17964607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2007.09.025
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