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Characterization and crystallization of a minimal catalytic core domain from mammalian type II adenylyl cyclase.

Adenylyl cyclases play a pivotal role in signal transduction by carrying out the regulated synthesis of cyclic AMP. The nine cloned mammalian adenylyl cyclases all share two conserved regions of sequence, C1 and C2, which are homologous to each other and are together responsible for catalytic activi...

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Detalhes bibliográficos
Main Authors: Zhang, G., Liu, Y., Qin, J., Vo, B., Tang, W. J., Ruoho, A. E., Hurley, J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144761/
https://ncbi.nlm.nih.gov/pubmed/9098900
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