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Viral caspase inhibitor p35, but not crmA, is neuroprotective in the ischemic penumbra following experimental stroke

Apoptosis, a predominant cause of neuronal death after stroke, can be executed in a caspase-dependent or apoptosis inducing factor (AIF)-dependent manner. Herpes Simplex Virus (HSV) vectors expressing caspase inhibitors p35 and crmA have been shown to be neuroprotective against various excitotoxic i...

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Detalhes bibliográficos
Main Authors: Sung, Jae Hoon, Zhao, Heng, Roy, Madhuri, Sapolsky, Robert M., Steinberg, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144739/
https://ncbi.nlm.nih.gov/pubmed/17945431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.07.030
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