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Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke

BACKGROUND: Ischemic stroke is a devastating condition, with metabolic derangement and persistent inflammation enhancing the initial insult of ischaemia. Recombinant tissue plasminogen remains the only effective treatment but limited as therapy must commence soon after the onset of symptoms. PURPOSE...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: So, Po-Wah, Ekonomou, Antigoni, Galley, Kim, Brody, Leigh, Sahuri-Arisoylu, Meliz, Rattray, Ivan, Cash, Diana, Bell, Jimmy D
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430000/
https://ncbi.nlm.nih.gov/pubmed/30936698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S193965
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