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Delayed activation of caspase-independent apoptosis during heart failure in transgenic mice overexpressing caspase inhibitor CrmA

Although caspase activation is generally thought to be necessary to induce apoptosis, recent evidence suggests that apoptosis can be activated in the setting of caspase inhibition. In this study, we tested the hypothesis that caspase-independent apoptotic pathways contribute to the development of he...

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Detalhes bibliográficos
Main Authors: Bae, Soochan, Siu, Parco M., Choudhury, Sangita, Ke, Qingen, Choi, Jun H., Koh, Young Y., Kang, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993210/
https://ncbi.nlm.nih.gov/pubmed/20833960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00168.2010
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