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Charge-charge interactions influence the denatured state ensemble and contribute to protein stability.

Several recent studies have shown that it is possible to increase protein stability by improving electrostatic interactions among charged groups on the surface of the folded protein. However, the stability increases are considerably smaller than predicted by a simple Coulomb's law calculation,...

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Bibliografske podrobnosti
Main Authors: Pace, C. N., Alston, R. W., Shaw, K. L.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144688/
https://ncbi.nlm.nih.gov/pubmed/10933506
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