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Post-translational modification is essential for catalytic activity of nitrile hydratase.

Nitrile hydratase from Rhodococcus sp. N-771 is an alphabeta heterodimer with a nonheme ferric iron in the catalytic center. In the catalytic center, alphaCys112 and alphaCys114 are modified to a cysteine sulfinic acid (Cys-SO2H) and a cysteine sulfenic acid (Cys-SOH), respectively. To understand th...

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Bibliografiske detaljer
Main Authors: Murakami, T., Nojiri, M., Nakayama, H., Odaka, M., Yohda, M., Dohmae, N., Takio, K., Nagamune, T., Endo, I.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144646/
https://ncbi.nlm.nih.gov/pubmed/10850812
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