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Solution NMR studies of apo-mSin3A and -mSin3B reveal that the PAH1 and PAH2 domains are structurally independent

The evolutionarily conserved mammalian Sin3 (mSin3) transcriptional corepressor interacts with a diverse array of transcription factors mainly through two PAH (paired amphipathic helix) domains located near the N terminus. Previous studies suggested the possibility of interdomain interactions involv...

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Detalhes bibliográficos
Main Authors: He, Yuan, Radhakrishnan, Ishwar
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144601/
https://ncbi.nlm.nih.gov/pubmed/18042683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073097308
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