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Microscopic stability of cold shock protein A examined by NMR native state hydrogen exchange as a function of urea and trimethylamine N-oxide.

Native state hydrogen exchange of cold shock protein A (CspA) has been characterized as a function of the denaturant urea and of the stabilizing agent trimethylamine N-oxide (TMAO). The structure of CspA has five strands of beta-sheet. Strands beta1-beta4 have strongly protected amide protons that,...

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Bibliografiska uppgifter
Huvudupphovsmän: Jaravine, V. A., Rathgeb-Szabo, K., Alexandrescu, A. T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144546/
https://ncbi.nlm.nih.gov/pubmed/10716181
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