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Structural changes in alpha-synuclein affect its chaperone-like activity in vitro.
Alpha-synuclein, a major constituent of Lewy bodies (LBs) in Parkinson's disease (PD), has been implicated to play a critical role in synaptic events, such as neuronal plasticity during development, learning, and degeneration under pathological conditions, although the physiological function of...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2000
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2144529/ https://ncbi.nlm.nih.gov/pubmed/11206070 |
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