Cargando...

Temperature-Dependent Structural Changes of Parkinson's Alpha-Synuclein Reveal the Role of Pre-Existing Oligomers in Alpha-Synuclein Fibrillization

Amyloid fibrils of α-synuclein are the main constituent of Lewy bodies deposited in substantial nigra of Parkinson's disease brains. α-Synuclein is an intrinsically disordered protein lacking compact secondary and tertiary structures. To enhance the understanding of its structure and function r...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ariesandi, Winny, Chang, Chi-Fon, Chen, Tseng-Erh, Chen, Yun-Ru
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551866/
https://ncbi.nlm.nih.gov/pubmed/23349712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053487
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!