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The structure of serine hydroxymethyltransferase as modeled by homology and validated by site-directed mutagenesis.

We describe a model for the three-dimensional structure of E. coli serine hydroxymethyltransferase based on its sequence homology with other PLP enzymes of the alpha-family and whose tertiary structures are known. The model suggests that certain amino acid residues at the putative active site of the...

詳細記述

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書誌詳細
主要な著者: Pascarella, S., Angelaccio, S., Contestabile, R., Delle Fratte, S., Di Salvo, M., Bossa, F.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144154/
https://ncbi.nlm.nih.gov/pubmed/9761478
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