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Comparative analysis of the noncollagenous NC1 domain of type IV collagen: identification of structural features important for assembly, function, and pathogenesis.

Type IV collagen alpha1-alpha6 chains have important roles in the assembly of basement membranes and are implicated in the pathogenesis of Goodpasture syndrome, an autoimmune disorder, and Alport syndrome, a hereditary renal disease. We report comparative sequence analyses and structural predictions...

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Hlavní autoři: Netzer, K. O., Suzuki, K., Itoh, Y., Hudson, B. G., Khalifah, R. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144033/
https://ncbi.nlm.nih.gov/pubmed/9655338
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