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Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes.

Proteolytic enzymes are synthesized as inactive precursors, or "zymogens," to prevent unwanted protein degradation, and to enable spatial and temporal regulation of proteolytic activity. Upon sorting or appropriate compartmentalization, zymogen conversion to the active enzyme typically inv...

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Bibliographic Details
Main Authors: Khan, A. R., James, M. N.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143990/
https://ncbi.nlm.nih.gov/pubmed/9568890
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