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Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.

The substitution of methionines with leucines within the interior of a protein is expected to increase stability both because of a more favorable solvent transfer term as well as the reduced entropic cost of holding a leucine side chain in a defined position. Together, these two terms are expected t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lipscomb, L. A., Gassner, N. C., Snow, S. D., Eldridge, A. M., Baase, W. A., Drew, D. L., Matthews, B. W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143956/
https://ncbi.nlm.nih.gov/pubmed/9541409
Tagiau: Ychwanegu Tag
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