A test of the "jigsaw puzzle" model for protein folding by multiple methionine substitutions within the core of T4 lysozyme.

To test whether the structure of a protein is determined in a manner akin to the assembly of a jigsaw puzzle, up to 10 adjacent residues within the core of T4 lysozyme were replaced by methionine. Such variants are active and fold cooperatively with progressively reduced stability. The structure of...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gassner, N C, Baase, W A, Matthews, B W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37959/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12155
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!