Regulation and crystallization of phosphorylated and dephosphorylated forms of truncated dimeric phenylalanine hydroxylase.

Phenylalanine hydroxylase is regulated in a complex manner, including activation by phosphorylation. It is normally found as an equilibrium of dimeric and tetrameric species, with the tetramer thought to be the active form. We converted the protein to the dimeric form by deleting the C-terminal 24 r...

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Detalhes bibliográficos
Main Authors: Kobe, B., Jennings, I. G., House, C. M., Feil, S. C., Michell, B. J., Tiganis, T., Parker, M. W., Cotton, R. G., Kemp, B. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143721/
https://ncbi.nlm.nih.gov/pubmed/9194198
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