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Crystallographic analysis of the pH-dependent binding of iminobiotin by streptavidin.
Streptavidin binds 2'-iminobiotin in a pH-dependent fashion--affinity decreases as the pH is lowered. This property makes the purification of compounds conjugated to streptavidin or immobiotin possible under mild conditions by affinity chromatography. In order to understand the molecular detail...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
1997
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2143720/ https://ncbi.nlm.nih.gov/pubmed/9194195 |
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