De novo heme proteins from designed combinatorial libraries.

We previously reported the design of a library of de novo amino acid sequences targeted to fold into four-helix bundles. The design of these sequences was based on a "binary code" strategy, in which the patterning of polar and nonpolar amino acids is specified explicitly, but the exact ide...

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Autori principali: Rojas, N. R., Kamtekar, S., Simons, C. T., McLean, J. E., Vogel, K. M., Spiro, T. G., Farid, R. S., Hecht, M. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143607/
https://ncbi.nlm.nih.gov/pubmed/9416601
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